Summers and Biggers (2003) suggested that,
“manufacturers of human embryo culture media follow either the ‘back to nature’
sequential or the ‘let the embryo choose’ global single-step philosophy or
an empirical optimization approach” (Summers and Biggers, 2003). There isn’t
any evidence to suggest which media is preferably better, however, depending on
the culture system and other factors, there can be a preference. Table 1
highlights the importance of both mediums in relation to embryonic development. 


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